Information: NIBIO
D-Serine is useful for the rapid and precise measurement of kidney function
Dec. 7, 2021
A team of researchers led by Tomonori Kimura, director of Center for Rare Disease Research, established a new method to measure glomerular filtration rate (GFR), a primary kidney function, by calculating the clearance of d-serine.
The research group evaluated the clearance of d-serine when assessing GFR through the inulin clearance measurement in living kidney transplant donors and recipients. Consequently, they found that the d-serine clearance strongly correlated with GFR and was less biased than the creatinine clearance, a conventional marker for renal function.
d-Amino acids, long-term undetected enantiomer (chiral body) of serine, is showing a great potential as biomarker of key kidney function and diseases. Chronic kidney disease is a global problem with more than 800 million patients in the world. d-Serine may solve the main problem of kidney disease.
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