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Project for Food Functionality
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The main target disease of this study is atherosclerosis, an underlying
disease of various cardiovascular diseases. Using animal model, this study
aims to explore the functional food components with the inhibitory effects
against atherosclerosis, as well as to identify the effective and safe
intakes of these components.
Food components examined for this study are n-3 fatty acid (e.g. docosahexaenoic
acid), Sesamin derived from sesame seeds, antioxidants etc., that reduce
various risk factors of atherosclerosis. The combined effects of these
functional factors are also investigated, which can be the screening test
for developing antiatherosclerotic functional foods. Likewise, with respect
to the suppression of developing atherosclerosis, the associations with
inflammation as well as the inhibitory factors of endothelial cell injury
are investigated. It is expected that the findings of this study will be
utilized for the development of novel antiatherosclerotic foods.
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