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国立研究開発法人 医薬基盤・健康・栄養研究所

ホーム > バイオ創薬プロジェクト > 研究実績 2006

研究実績 2006

2006

原著論文

鎌田 春彦

Imai S., Mukai Y., Nagano K., Shibata H., Sugita T., Abe Y., Nomura T., Tsutsumi Y., Kamada H., Nakagawa S., Tsunoda S.
Quality enhancement of the non-immune phage scFv library to isolate effective antibodies.
Biol. Pharm. Bull., 29(7): 1325-1330, 2006. [PubMed]

Mukai Y., Sugita T., Yamato T., Yamanada N., Shibata H., Imai S., Abe Y., Nagano K., Nomura T., Tsutsumi Y., Kamada H., Nakagawa S., Tsunoda S.
Creation of novel protein transduction domain (PTD) mutants by a phage display-based high-throughput screening system.
Biol. Pharm. Bull., 29(8): 1570-1574, 2006. [PubMed]

Kawamura M., Shibata H., Okamoto T., Mukai Y., Sugita T., Abe Y., Imai S., Nomura T., Nagano K., Mayumi T., Nakagawa S., Tsutsumi Y., Kamada H., Tsunoda S.
A novel method for construction of gene fragment library to searching epitopes.
Biochem. Biophys. Res. Commun., 346: 198-204, 2006. [PubMed]

Mukai Y., Okamoto T., Kawamura M., Shibata H., Sugita T., Imai S., Abe Y., Nagano K., Nomura T., Kamada H., Tsutsumi Y., Mayumi T., Nakagawa S., Tsunoda S.
Optimization of anti-tumor necrosis factor-alpha single chain Fv displayed on phages for creation of functional antibodies.,
Pharmazie., 61: 889-890, 2006. [PubMed]

永田 諭志

Onda M,* Nagata S,* FitzGerald DJ, Beers R, Fisher RJ, Vincent JJ, Lee B, Nakamura M, Hwang J, Kreitman RJ, Hassan R and Pastan I (2006) Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients. The Journal of Immunology 177, 8822-8834. (*equal contribution acknowledged)[PubMed]

Lee Y, Ise T, Ha D, Saint FA, Hahn Y, Liu XF, Nagata S, Lee B, Bera TK, Pastan I  (2006) Evolution and expression of chimeric POTE-actin genes in the human genome. Proceedings of National Academy of Sciences of the United States of America 103, 17885-17890.[PubMed]

Onda M, Nagata S, Ho M, Bera TK, Hassan R, Alexander RH, Pastan I (2006) Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma. Clin Cancer Res 12, 4225-4231.[PubMed]

Ho M, Nagata S, Pastan I (2006) Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. Proc Natl Acad Sci U S A 103, 9637-9642.[PubMed]

Ise T, Kreitman RJ, Pastan I, Nagata S (2006) Sandwich ELISAs for soluble immunoglobulin superfamily receptor translocation-associated 2 (IRTA2)/FcRH5 (CD307) proteins in human sera. Clin Chem Lab Med 44, 594-602.[PubMed]

Egland KA, Liu XF, Squires S, Nagata S, Man YG, Bera TK, Onda M, Vincent JJ, Strausberg RL, Lee B, Pastan I (2006) High expression of a cytokeratin-associated protein in many cancers. Proc Natl Acad Sci U S A 103, 5929-5934.[PubMed]

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